白藜芦醇介绍

Anti Aging Discoveries (参考译文)

参考译文:

白藜芦醇可抗衰老

在众多的抗衰老发现中,白藜芦醇被证明是一种很有效的成分。它的好处仍在被广泛研究,但目前所知道的包括有:

a.    抑制消化道中的有害细菌的扩散

b.     预防心血管疾病

c.    减少冠心病的发病率

d.     防止低密度脂蛋白(坏胆固醇)氧化

e.    抗氧化作用及增强免疫力

目前有很多的关于白藜芦醇的研究,然而,正如我们所指出的那样,新的研究结果不断涌现,很多是从人体的试验当中得出的。

芭芭拉·沃尓特的抗衰老发现
芭芭拉·沃尓特最近作了关于白藜芦醇和红酒的抗衰老作用的报告。我们为什么会衰老?我们可以如何减慢或控制衰老呢?请看下面芭芭拉·沃尓特新的抗衰老发现:

芭芭拉的报告表明,目前媒体关于白藜芦醇的报道都是关于抗衰老的。通过激活身体里面的某种细胞,白藜芦醇促使人体能够更好地“照顾自己”。这正是今天的其中一个抗衰老发现。

白藜芦醇可延长寿命
Newsweek中的一篇报道说,一个研究小组在《自然》杂志中发表了白藜芦醇对哺乳动物的寿命影响的首次研究。研究中用3种不同的饮食方式把小鼠分成3组:(1)标准饮食;(2)高卡路里高脂肪饮食;(3)高卡路里高脂肪饮食,但以白藜芦醇作为补充剂。

研究结果表明,与标准饮食的小鼠相比,高卡路里高脂肪饮食的小鼠体重增加,出现脂肪肝、心脏疾病及糖尿病等症状,并在幼年死忙。然而,高卡路里高脂肪饮食但有白藜芦醇作为补充剂的小鼠并没有出现如此症状。

白藜芦醇与骨骼健康
我很惊喜地发现很多关于白藜芦醇对骨骼健康的研究。
在2001年,科学时报“药物试验及临床研究”的报道中刊登了一份由Creighton 大学的研究人员共同执行的题为“白藜芦醇与女性健康”的研究。研究中总结了白藜芦醇可能是比HRT 更好的一种心血管及骨质疏松预防剂。

该研究结果在2008年被一份名为“Cell Metabolism”的杂志又一次证实了。在研究中,从厚度、骨质含量、矿物质及密度、柔韧性等方面看,有服用白藜芦醇的小鼠明显比没有服用白藜芦醇的小鼠有着更健康的骨骼。

白藜芦醇或能用于增强骨质密度
以Katherine Tucker为首的国际专家小组在Framingham Offspring的研究中研究酒精摄取量与骨质密度的关系。他们总结出适量的酒精摄取量的确能使骨骼更健康。

美国营养协会的主席Stephanie Atkinson医生博士根据研究的结果,指出是骨骼健康的主要因素应归功于啤酒中的硅和红酒中的白藜芦醇。

但她指出,酒精的摄入必须适量,应避免过量摄入。

白藜芦醇可防止动脉粥样硬化
动脉粥样硬化,就是我们常说的动脉硬化,在2009年3月12日的New England Journal of Medicine中有过详细的介绍。

研究中发现,动脉堵塞可以由抗氧化物来治疗。尤其当低密度脂蛋白胆固醇在动脉中堵塞后,白藜芦醇可以使其再次移动。“最近的一份研究表明,泡沫状细胞通过与氧化低密度脂蛋白发生反应而堵塞动脉,可以通过抗氧化物,如白藜芦醇,使其能够再次移动。

研究人员用白藜芦醇作为抗氧化物对付动脉硬化,发现原来的堵塞的动脉变通畅了。

白藜芦醇可以帮助治疗炎症
在加利福利亚洲的Wester 人类研究中心的一位名为 Dianiel H Hwang 的分子生物学家一直在从事一项白藜芦醇对抗炎症的研究。

他的研究结果完全是科学的。他指出,白藜芦醇可以干扰一种叫TBK1和RIP1的分子与蛋白质结合引发炎症。白藜芦醇就是通过阻止这些分子与TLR蛋白质结合而减少炎症的发生。国际神经化学杂志刊登了关于白藜芦醇有助于对抗衰老的报道。白藜芦醇能帮助减少血小板在大脑中的形成。Cornell大学研究揭示了白藜芦醇能控制人体大脑中的很多自然衰老过程。

白藜芦醇研究奖项
在2009年4月的NYU 年度奖座谈会中,麻省理工学院的 Leonard P. Guarente 获得了生物科技领域的杰出工程师奖。

他发现了 sirtuin 是生物长寿的关键物质。自此以后,利用白藜芦醇激活 sirtuin 已成为科学家研究生命长寿的课题。

原文链接:http://www.benefits-of-resveratrol.com


英文原文:
Among all the anti aging discoveries, resveratrol is the soup-du-jour at the moment. The benefits of resveratrol are still being studied but so far include:

a.     Stopping the proliferation of bad bacteria in the digestive tract

b.     Prevention of cardiovascular disease

c.     Reduction of the incidence of coronary heart disease

d.     Protection of cells against degradation of low-density lipoproteins

e.     Effective antioxidant and immunity protection.

Most of the research on Resveratrol has been done in the laboratory so far. Nevertheless, as we point out, the results of new studies are constantly coming forward every week - many from human trials.

Barbara Walter's Anti Aging Discovery
Barbara Walters recently reported on the resveratrol and red wine research as it pertains to the aging question. Why do we age and how do we slow or stop that process? Watch here what Barbara Walters learned about these new anti aging discoveries:

Barbara's report shows that the current topic behind Resveratrol media exposure is Longevity. By activating certain genes in the body, Resveratrol "tricks" the body into taking better care of itself. Truly one of today's anti aging discoveries.

Resveratrol Increases Lifespan
An article in Newsweek state that a research team reported in the journal Nature the first study of the effect of resveratrol on the life span of a mammal. The study compared three sets of mice on three different diets (1) a standard diet (2) a high-calorie, high-fat diet and (3) a high-calorie, high-fat diet supplemented with resveratrol.

The study concluded that compared to the standard diet mice (1) the mice with the high-calorie, high-fat diet (2) gained weight, developed fatty livers, inflammation of the heart and diabetes-like symptoms dying at a younger age. However, the mice on the high-calorie, high-fat diet supplemented with resveratrol (3) had none of these complications.

Experts disagree as to when we'll know the final result and how much life we'll gain with resveratrol, but few dispute it will be positive. Steve Austad, the most outspoken on the subject, believes it will be 30 years before the facts are on paper. Most other scientists who have weighed in estimate 5 years at the outset. To add more fuel to the fire, 60 Minutes spent an hour learning about the resveratrol research that has propelled it to be one of the most important anti aging discoveries.

Resveratrol and Bone Health
I was pleasantly surprised to find so many studies on bone health that reflected positively on resveratrol.

In 2001 the Scientific Journal "Drugs Under Experimental and Clinical Research" published a study, "Benefits of resveratrol in women's health" by Researchers at Creighton University in Omaha, Nebraska. That study concluded resveratrol therapy might be a better alternative than HRT for cardio and osteoporosis protection.

The results of that study were mimicked in a 2008 in a Journal called "Cell Metabolism". That study, on mice, showed the mice on resveratrol drugs had better bone healthy, as measured by thickness, volume, mineral content and density, and bending stiffness compared to the non-treated control group.

Resveratrol May Contribute to Improved Bone Density
An international team of experts headed by Katherine Tucker, studied the association between alcohol consumption and bone density in the Framingham Offspring Study. They concluded that moderate consumption of alcohol make make your bones stronger.

Analyzing the study, Dr. Stephanie Atkinson, Professor, Department of Pediatrics, and President of the American Society of Nutrition, stated that the positive effect might be attributed to bone preserving ingredients like silicon in beer and resveratrol in red wine - in addition to the alcohol.

As always, she also said any consumption of alcohol must be weighed against the risks associated with excessive use.

Resveratrol Prevents Atherosclerosis
Atherosclerosis, which most of us refer to as hardening of the arteries, was featured in the March 12th, 2009 New England Journal of Medicine.

The study found that clogged arteries could be reversed with antioxidant therapy. Specifically, the LDL cholesterol that was building up in the arteries was made mobile again after the introduction of resveratrol.

"A recent study by Park and Colleagues showed that these foam cells are trapped by interaction with oxidized low-density lipoprotein (LDL) and can be re-mobilized by dynamic exposure to key antioxidants such as resveratrol.

The researchers subjected the hardened arteries to resveratrol antioxidants and the blockages began to break up.

Resveratrol Helps Stop Inflammation
Daniel H Hwang, a research molecular biologist in the Agricultural Research Services at the Wester Human Nutrition Research Center in Davis, California has been doing resveratrol research in terms of its affects on inflammation.

While his study results are entirely scientific, he's determined that resveratrol interferes with molecules (called TBK1 and RIP1) that communicate with the proteins that cause inflammation. By impeding the communication between these molecules and the TLR proteins, resveratrol helps reduce inflammation. A study published in the International Journal of Neurochemistry demonstrated the potential for resveratrol to aid in the fight against aging. It demonstrated that resveratrol helped to reduce the formation of plaque build up in the brain. Commissioned by Cornell University, the study sheds light into the way resveratrol can help control many of the natural effects of aging on the brain.

Resveratrol Research Gets Award from NYU
At the April, 2009 NYU Annual Awards Symposium, Leonard P. Guarente of MIT will be awarded as an Outstanding Pioneer in the Field Of Biotechnology.

Specifically, Mr Guarente discovered that sirtuins were the key regulators of longevity in living creatures. Since then activation of the sirtuins by resveratrol has led to trials of it analogues as scientists search for the key to longer life.